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Unpicking the grammar of genes

(Medical Xpress) -- The MHC on the short arm of chromosome 6 is the most gene-dense region of our DNA with around 230 genes all crammed into this stretch of our genome.

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New genetic risk factors of lupus found in study of African-American women

Researchers from Boston University's Slone Epidemiology Center have found four new genetic variants in the major histocompatibility complex (MHC) that confer a higher risk of systemic lupus...

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From genomic data to new cancer drug

New discoveries about follicular lymphoma, a currently intractable form of cancer, highlight the power of functional genomics in cancer gene discovery. A report in the Oct 28th issue of Cell...

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Two unique studies indentify three genetic regions associated with schizophrenia

(Medical Xpress) -- Two new independent research groups looking to find the genetic roots of schizophrenia and bipolar disorder have found evidence of variations in regions of the human genome that...

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New gene variants raise risk of neuroblastoma, influence tumor progression

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of...

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Study investigates genetic variants' role in increasing Parkinson's disease risk

Boston University School of Medicine (BUSM) investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in...

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Scientists deepen genetic understanding of MS

(Medical Xpress)—Five scientists, including two from Simon Fraser University, have discovered that 30 per cent of our likelihood of developing Multiple Sclerosis (MS) can be explained by 475,806...

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Gene associated with adolescent idiopathic scoliosis identified

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and...

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Cancer: Lymphoma-linked risk factor identified

Follicular lymphoma is often caused by a translocation between chromosomes 14 and 18, resulting in the overexpression of a cancer-causing gene called BCL-2. A research team co-led by A*STAR scientists...

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